Ethoxysuccinato-cisplatin
WebJun 28, 2016 · Cisplatin (cis-diaminodichloroplatinum) was the first platinum based antineoplastic agent developed in 1970s. Since then it has been widely used in … WebThe nanoparticles displayed extended half-lives of the loaded drug, disuccinatocisplatin, for 9 h. In vitro cancer cell cytotoxicity studies on a human colon carcinoma cell line (HT- 29) further...
Ethoxysuccinato-cisplatin
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WebMay 2, 2024 · For instance, anticancer drugs including doxorubicin [34,35,36,37], cisplatin , topotecan , camptothecin , and 5-fluorouracil have been incorporated into MOFs for intracellular delivery and cancer treatment. Some near-infrared ... For instance, ethoxysuccinato-cisplatin anticancer prodrug was post-synthetically loaded into MIL … WebMetal-Organic Frameworks (MOFs) have been recently used as potential nanocarrier platforms in biomedical applications such as drug storage and delivery, due to their low toxicity, biodegradability, high internal surface area, widely tunable composition, high payloads and controlled drug release.
WebFeb 7, 2024 · In proof-of-concept expts., an optical contrast agent (a BODIPY dye) and an ethoxysuccinato-cisplatin anticancer prodrug were successfully incorporated into the Fe(III)-carboxylate NMOFs via postsynthetic modifications of the as-synthesized particles. These cargoes are released upon the degrdn. of the NMOF frameworks, and the rate of … WebMay 1, 2024 · In this study, we have prepared the series of nanohybrids of Cr-based metal-organic framework (Cr-MOF) and cobalt phthalocyanine (CoPc) nanoparticles (denoted as [email protected]) and ...
WebSep 1, 2011 · In proof-of-concept experiments, an optical contrast agent (a BODIPY dye) and an ethoxysuccinato-cisplatin anticancer prodrug were successfully incorporated into the Fe(III)-carboxylate NMOFs via ... WebSep 24, 2024 · to cisplatin, making carboplatin a suitable drug for higher-dose chemotherapy in some types of cancers [ 50 ]. The knockout of CTR1 from the cells causes an important effect on cells at a low con-
WebMar 1, 2024 · Abstract and Figures Metal-organic frameworks (MOFs), comprised of organic ligands and metal ions/metal clusters via coordinative bonds are highly porous, crystalline materials. Their tunable...
WebFeb 1, 2024 · In his scicentific report the authors have claimed increased biological stability of ethoxysuccinato-cisplatin coated with silica reported due to reduction of degradation silica coated NMOFs in cellular enviroments. burger and beer la quintaWebThe ethoxysuccinato-cisplatin (ESCP) prodrug, c,c,t-[PtCl2(NH3)2(OEt)(O2CCH2CH2CO2H)], was first activated by 1,1-carbonydiimidazole … halloween mackinac islandWebApr 1, 2010 · The ability to reduce a relatively nontoxic prodrug to a highly potent anticancer drug in such a delivery scheme is very attractive since it facilitates selective delivery of … halloween magazine 2022WebOct 1, 2009 · We also loaded a prodrug of cisplatin into 1a by post-synthetic modification. The ethoxysuccinato-cisplatin (ESCP) prodrug, c,c,t -[PtCl 2 (NH 3 ) 2 (OEt)(O 2 CCH … burger and barley rock hillWebLin et al. utilized simple coupling chemistry to covalently link cisplatin (IV) precursor, ethoxysuccinato-cisplatin to Fe(III)-carboxylate nanoscale metal-organic frameworks … halloween magazine 2021WebSep 16, 2009 · In proof-of-concept experiments, an optical contrast agent (a BODIPY dye) and an ethoxysuccinato-cisplatin anticancer prodrug were successfully incorporated … burger a montrealWebNanoscale metal–organic frameworks (NMOFs) are an interesting and unique class of hybrid porous materials constructed by the self-assembly of metal ions/clusters with organic linkers. The high storage capacities, facile synthesis, easy surface functionalization, diverse compositions and excellent biocompatib Recent Open Access Articles Journal of … halloween magazine ads