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Krt5-cre

Web21 dec. 2024 · The use of different murine Cre lines (Lgr5-Cre ERT2, Krt5-Cre ERT2 or Krt14-Cre to target BCs; Bgl-Cre or Wap-Cre to trace ERα neg LCs; and Esr1-Cre to monitor ERα pos LCs) to induce the expression of specific mutations in different mammary epithelial cell types resulted in the generation of tumors that resembled some of the … Web品系说明：KRT5基因理论表达系统/组织：其他； 理论标记细胞类型：表皮基底细胞，眼角膜，食管上皮，前列腺，膀胱，部分自发乳腺癌和肺癌细胞等 基因官方名：KRT5,Krt5,iCre 基因全名：keratin 5,keratin 5 基因别名：K5,CK5,Tfip8,Krt2-5,AW146334,3300001P10Rik NCBI： 281268#110308 染色体：Chr 11 销售状态：IF (正常销售) 保存方式： 冷冻 品系 …

Frontiers Physiological Functions of Mcl-1: Insights From Genetic ...

Web10 jul. 2024 · Krt5-Cre transgenic line in which Cre recombinase is driven by the HBC specific Krt5 promoter was crossed to RelA flox/flox mice to generate RelA deletion in HBCs. The Rosa26-stop flox/flox -td-Tomato strain was provided by Xinzhong Dong, Johns Hopkins Medicine. Web20 feb. 2024 · These mice were then inbred. Offspring that carried Krt5-Cre +/– Hsd11b1 flox/flox were used for further analysis as conditional knockouts (HSD11b1 KC–/–). Krt5-Cre +/– Hsd11b1 +/+ littermates and C57BL6/J mice purchased from Japan CLEA (Osaka, Japan) were used as WT in two experiments, respectively, and reproducibility of data … mass in cats stomach area https://prodenpex.com

Skin γδ T cell inflammatory responses are hardwired in the thymus …

WebFigure 1. Preliminary method for culturing alveolar organoids results in basal outgrowth. (A) Flow cytometry-based quantification of Sftpc-eGFP-expressing cells over time in organoid culture under preliminary culture conditions.A total of n = 2 independent lines was established from Sftpc-eGFP mice. (B) GSEA enrichment plots of AT2 and basal cell … Web13 apr. 2024 · This context was mimicked by examining release from cytostatic doses of the dual ErbB inhibitor, lapatinib, in TM15 clone 6 (TM15c6) cells derived from an Erbb2-amplified tumor of a P MMTV-Cre ... WebThe genotyping protocol (s) presented here have been optimized for reagents and conditions used by The Jackson Laboratory (JAX). To genotype animals, JAX … hydropower small scale

Acute inflammation regulates neuroregeneration through the NF …

Category:JCI - Basal epithelial stem cells cross an alarmin checkpoint for ...

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Krt5-cre

Nature 头颈肿瘤中p53缺失导致神经元重塑-微信文章-仪器谱

Web3 dec. 2014 · 角蛋白 信息学 基因 人类 生物 keratin. 人类角蛋白14 (KRT14)基因的生物信息学分析前言：角蛋白14 (Keratin 14 K14)是角蛋白家族中一员，与角蛋白5组成一组角蛋白对。. 在正常胎儿和成人皮肤内，K14 的转录和翻译主要在表皮基底层和毛囊进行。. 角蛋 白（keratin ）系硬 ... Web24 aug. 2024 · A distinct feature of Krt5-Cre-Ert2 Il33 fl/fl mice was the capacity for attenuation of PVLD despite a preserved induction of Il33 expression . This combination was distinct from disease blockade in Il33 –/– mice, raising the possibility that basal cells might be activated to also influence IL-33–responsive immune cells.

Krt5-cre

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Web证明Krt5- (IRES-CreERT2)小鼠可以成为实现Krt阳性细胞特异性敲除或表达的工具鼠。. 图 2 Tamoxifen 诱导后，Krt5 CreERT2/+; Rosa26 tdTomato/+ 小鼠各组织中tdTomato的表达 … WebB6N.129S6 (Cg)- Krt5 tm1.1 (cre/ERT2)Blh /J Stock No: 029155 Protocol 19562: Separated PCR Assay - Krt5 Alternate3 Version 1. 0 Notes The genotyping …

WebKRT5 is part of cluster 11 Squamous epithelial cells - Epithelial cell function with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated … WebSummary of KRT5 (EBS2, KRT5A) expression in human brain tissue. Cytoplasmic and membranous expression in squamous and respiratory epithelia as well as glandular cells of salivary gland, male genitalia and breast.

WebSUMMARYBasal cells are multipotent stem cells of a variety of organs, and in the lung are known as crucial components of the airway epithelium. However, it remains unclear how diverse basal cells are and whether distinct subpopulations respond Web19 okt. 2024 · Deletion of ARL13B in epididymal basal cells results in shorter primary cilia and reduced Hedgehog signaling. A Krt5 Cre; Arl13b fl/fl conditional knock-out mice (cKO) were generated and compared to littermate control mice (Ctl1, referred as Ctl thereafter, or Ctl2 genotypes). B ARL13B was quantified by western blot from bulk epididymal protein …

Web1 nov. 2024 · Krt5 Cre ERT2-Gt (ROSA)26Sor tm4(ACTB-tdTomato-EGFP) mice were used to perform lineage tracing. For induction of Cre-ERT2 protein, 8–10-week-old mice were injected with tamoxifen dissolved in corn oil via an intra-peritoneal route. For each mouse, 0.1 mg tamoxifen was used to label single cells (Kusaba et al. 2014; Kang et al. 2016).

WebAn analysis of iNKT cell development in CD4-cre;A20 F/F mice using the aforementioned alternate NKT cell developmental scheme revealed a selective reduction in NKT1 a thymocytes in CD4-cre;A20 F/F ... mass in cheek areaWeb9 jan. 2024 · 细数肿瘤免疫研究中 5 大小鼠模型，让你少查半个月文献. 2024-01-09 12:02. 2013 年《Science》杂志评选的当年十大科学突破中，癌症免疫治疗研究成果位列其首！. 2024 年的诺贝尔生理医学奖授予了开启肿瘤免疫治疗新航向的美国免疫学家詹姆斯 · 艾利 … mass in cats mouthWebTg (KRT5-cre/ERT2)2Ipc Transgene Detail MGI Mouse (MGI:2177429) More Phenotypes Phenotypes, Alleles & Diseases Query Human Phenotype (HPO) Browser More Gene … mass in chineseWeb7 mrt. 2024 · Krt5 keratin 5 [ (house mouse)] Gene ID: 110308, updated on 28-Dec-2024. Summary. Predicted to enable scaffold protein binding activity. Located in keratin … hydropower social impactWebThe second generation of inducible Cre-ERT recombinase, hemizygous B6.129S-Tg (UBC-cre/ERT2)1Ejb/J (hereafter abbreviated as Cre-ERT2), a fusion of a mutated estrogen receptor and Cre recombinase, was engineered to be more efficient and specific than the original Cre-ERT. mass in chest x rayWeb24 dec. 2014 · We posit that isolation using Krt5-driven Cre enriches for LNEPs that have undergone partial commitment to the Krt5 program, whereas surface marker-based selection represents a less biased approach. This is consistent with lineage analysis ( Fig. 1H ) indicating Krt5-CreERT2-traced cells can only account for a small fraction of the … mass in c beethovenWebCre 蛋白是一种重组酶，是causes recombination的缩写，于1981 年从 P1 噬菌体中被发现，属于 λInt 酶超基因家族。 Cre 重组酶基因编码区序列全长1029bp，编码 38kDa 蛋白 … hydropower sources